2026 College Football Week 2: Best Games To Watch This Weekend

Will history repeat itself in Saturday's Ohio State-Texas battle or will the Longhorns find a way to win? And which team will kick off the weekend with a spotless record after the Missouri-Kansas tilt? Here are the five must-watch college football games for Week 2.

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Spread: Missouri -5.5 Moneyline: Missouri -218; Kansas +180 O/U: 51.5 What To Know: Missouri rolled to an easy straight up (SU) win over Arkansas-Pine Bluff in Week 1.

However, the Tigers failed to cover the 54.5-point spread, as the final score was Mizzou 54, Pine Bluff 14.

This week, Missouri faces a tougher opponent in Kansas.

Unlike the Tigers, the Jayhawks covered the 41-point spread set in their game by defeating Long Island University 51-6.

When these two squads faced off last season at Missouri, the Tigers won 42-31.

"The Tigers have the better quarterback, and their run game is still rather awesome even without Ahmad Hardy in the backfield," FOX Sports college football writer RJ Young explained about his Mizzou-over-Kansas pick.

Spread: Oregon -23.5 Moneyline: Oregon -2100; OSU +1100 O/U: 57.5 What To Know: Oregon got a scare last week when Boise State kept it close well into the fourth quarter.

The Ducks ended up getting the 34-27 win but did not cover the 24.5-point spread.

Oklahoma State, on the other hand, lost to Tulsa in Week 1 24-10.

While the Cowboys controlled possession for more minutes, they had four turnovers and six penalties for 59 yards.