Ohio State snaps Indiana's 22-game winning streak, hands reigning champs first loss since 2024 in thriller

For the first time since December 2024, Indiana has lost a football game.

No.

4 Ohio State snapped Indiana's 22-game winning streak, beating No.

5 Indiana 19-15 despite losing star quarterback Julian Sayin to an injury on Saturday afternoon at Memorial Stadium.

It was Indiana's first home loss in 19 games.

Heisman frontrunner Jeremiah Smith scored a touchdown in the fourth quarter with a spectacular catch, and Ohio State's defense repeatedly stood tall during the fourth quarter, holding the reigning national champions at bay.

CLICK HERE FOR MORE OUTKICK SPORTS COVERAGE Ohio State bookended the first-half scoring.

Julian Sayin came out firing, quickly driving the Buckeyes into Indiana territory before the Hoosiers' defense stood tall and forced a field goal.

On the final possession of the first half, Sayin drove the Buckeyes into a goal-to-go situation.

The Hoosiers' defense shut Ohio State down on the first three plays, but Ryan Day decided to go for it.

Day's gamble paid off, as Sayin found a wide-open Bo Jackson in the flat for a touchdown, putting Ohio State up 10-7.

Indiana's lone touchdown in the first half came after a Sayin interception.

The Buckeyes quarterback's pass was intercepted deep in Ohio State territory, and two plays later, Hoosiers running back Turbo Richard scored on a 7-yard touchdown run.

Indiana once again drove into Ohio State territory and seemed primed to score, but kicker Nico Radicic's 32-yard field goal clanged off the upright.