10 health conditions may be linked to Alzheimer's years before diagnosis

Certain medical conditions may signal early-onset Alzheimer’s disease several years before diagnosis, a new Finnish study suggests.

Researchers found that depression , vertigo, headaches and other conditions were more common during the five years preceding diagnosis, potentially offering clues for earlier detection.

The researchers analyzed medical records from 407 people with early-onset Alzheimer’s disease and 4,035 people of similar age and sex without the diagnosis, focusing on the 15 years prior to diagnosis.

SUBTLE CHANGE IN HOW YOU SPEAK COULD BE EARLY SIGN OF DEMENTIA RISK, NEW RESEARCH SUGGESTS The average age at diagnosis was 60.

Early-onset disease is diagnosed in people under 65.

The findings were published in the journal Alzheimer’s & Dementia.

The following conditions were found to be significantly more prevalent among those who were ultimately diagnosed with early-onset Alzheimer’s.

DEMENTIA RISK MORE THAN QUADRUPLES AMONG ADULTS WITH COMMON DISORDER Differences in medical conditions were most pronounced in the five years before an early-onset Alzheimer's diagnosis, the study showed.

3 THINGS TO AVOID IN MIDDLE AGE COULD MEAN 13 MORE YEARS WITHOUT DEMENTIA, STUDY FINDS The researchers also found that healthcare visits increased substantially among early-onset Alzheimer’s patients immediately before and during the time of diagnosis, which may indicate emerging symptoms.

CLICK HERE FOR MORE HEALTH STORIES "It is well-known that the neuropathological changes associated with Alzheimer’s disease begin at least 15 to 20 years before clinical cognitive symptoms appear," said Suvi-Johanna Krüger, M.D., Ph.D., study co-author and clinical lecturer at University of Oulu, in a press release.

"Most previous studies have focused on late-onset Alzheimer’s disease, and considerably less is known about early-onset Alzheimer’s disease." As the study was observational, it only establishes associations and cannot demonstrate that these conditions can reliably predict Alzheimer's disease.

"Our study cannot determine whether these conditions cause early-onset Alzheimer’s disease or whether they are consequences of the underlying disease process," Krüger noted.

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER "Some conditions may represent risk factors, while others may reflect early symptoms or changes occurring during the prodromal phase of the disease." It is also possible that genetics , lifestyle and socioeconomic factors played a role in the patients’ outcomes.

Also, the researchers could not independently verify all medical diagnoses or assess the severity of the patients’ disease severity.